What is CREON?
CREON (pancrelipase) is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not release enough enzymes. This condition is called EPI (exocrine pancreatic insufficiency) and may be due to cystic fibrosis, chronic pancreatitis (swelling of the pancreas that lasts a long time), pancreatectomy (removal of some or all of the pancreas), or other conditions. Taken as prescribed, CREON replaces enzymes that your pancreas isn’t releasing, helping you digest fats, proteins, and carbohydrates (sugars) in food.
*Per Jan ‘22–Dec ’22 analysis of 12,690 GEs from Subnational XPO. 84% of surveyed GEs had >50% of their PERT prescriptions filled as CREON
How should I take CREON?
If your doctor prescribes you CREON, they will choose a dose that is specific for you, based on factors like your body weight and your diet—so make sure you take CREON exactly as your doctor tells you.
Take it. Track it. Talk about it.
Take CREON every time you eat
Take CREON every time you eat, whether it’s a full meal or snack. Don’t forget to take CREON with you when you’re on the go—especially when you’re eating out. Always take CREON with enough liquid to swallow your dose without crushing or chewing it.
Track your diet and symptoms
Keep track of what you are eating and how you are feeling. Tracking your diet and symptoms will help your doctor determine if your CREON dose needs to be adjusted. Get started with the Treatment Tracker.
Talk with your doctor
Communicate with your doctor and care team regularly and share how you’re feeling. It’s important to schedule follow-up visits, either via telehealth or in person to maintain an ongoing conversation about your symptoms.
- CAMILLE E. EPI patient
My life has changed since being diagnosed with EPI, but it has not stopped me from living. I still watch what I eat and have a healthy, balanced diet and take my CREON.
Your quick guide to EPI and CREON
It may seem like there's a lot to learn about EPI (exocrine pancreatic insufficiency) and CREON, but this brochure can help you navigate different topics and provide you with the answers you need as you're starting treatment.
Answers to frequently asked questions
CREON is often covered by insurance. Contact your insurance provider to find out if CREON is covered under your particular insurance policy. You may also be eligible to save money on your CREON prescription through the CREON
CREON does not cure EPI, but it can help replace the digestive enzymes that your pancreas no longer makes. These enzymes help break down fats, proteins, and carbohydrates in food.
The most common side effects include increased blood sugar levels (hyperglycemia) or decreased blood sugar levels (hypoglycemia), pain in your stomach area, frequent or abnormal bowel movements, gas, vomiting, dizziness, or sore throat and cough. Always thoroughly discuss the risks and benefits of CREON with your doctor.