Underlying conditions and procedures
Certain underlying conditions and surgical procedures affect the pancreas and may lead to EPI (exocrine pancreatic insufficiency).
Underlying conditions or procedures
that may lead to EPI
A chronic inflammatory disease of the pancreas, CP is the most common cause of EPI in adults.
An inherited genetic condition that leads to chronic disease, CF causes a thick, sticky mucus to be produced in certain organs. If this mucus clogs the pancreas and causes damage, making it difficult for digestive enzymes to reach the intestine, this can lead to EPI.
An operation to remove all or part of the pancreas, a pancreatectomy could limit or stop pancreatic digestive enzyme production or delivery leading to EPI.
Obstruction of the pancreatic duct by tumors, destruction of the pancreas by tumor growth, and loss of pancreatic tissue from surgery—all potential results of pancreatic cancer—can lead to EPI.
Other underlying conditions or procedures
in which EPI has been reported
A condition where the pancreas becomes inflamed, AP can lead to temporary or permanent EPI.
Though it is generally temporary and may improve with a gluten-free diet, celiac disease can lead to EPI.
By making your immune system attack your own pancreas, by damaging your pancreatic duct, and by scarring or inflaming your pancreas, Crohn’s disease can affect the ability of your pancreas to produce the enzymes you need to digest food. This can lead to EPI.
Potentially affecting how pancreatic digestive enzymes are delivered to break down food, certain surgeries of the stomach or intestines can lead to EPI.
The inability to produce insulin, a hormone produced by the pancreas that helps control blood sugar, Type 1 diabetes may also be an underlying condition that causes EPI.
In Type 2 diabetes blood sugar levels are too high because the body cannot make or use insulin well. EPI has been reported in patients with Type 2 diabetes.
Talk to your doctor if you have one or more symptoms
If you have been experiencing one, some, or all of the symptoms of EPI, make sure you let your doctor know as soon as possible.
to check your symptoms and share the results with your doctor. Please note that this quiz is not intended to provide a diagnosis or any treatment recommendations.
Answers to frequently
Because EPI affects your body’s ability to break down food, it may prevent you from absorbing enough nutrients, resulting in serious complications, such as malnutrition. That’s why it’s important to talk to your doctor if you think you might have EPI. If your doctor diagnoses you with EPI and prescribes a treatment, it’s important to continue taking it exactly as your doctor tells you.
Pancreatic enzyme replacement therapies (PERTs) are the standard of care for EPI. PERTs replace digestive enzymes that your body may be missing. Because PERTs help you digest food, they need to be taken every time you eat—with every meal and snack.