What is EPI?
EPI is a condition that occurs when the pancreas doesn’t make enough digestive enzymes.
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CREON (pancrelipase) is a prescription medicine used to treat EPI (exocrine pancreatic insufficiency). EPI is a condition where the pancreas doesn't release enough digestive enzymes to break down food. CREON works by replenishing the missing enzymes.
Getting started with CREON
Get tools and tips to help you start and stay on track with your CREON treatment plan.
Real patient stories
Hear what patients have to say about EPI and treatment with CREON.
Saving on CREON
Find out if you’re eligible to pay as little as $5 (or less) for your monthly CREON prescription.*
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Supporting you every step of the way
CREON's patient support programs provide you with:
- Financial savings on CREON*
- Multivitamins and nutritional products at no charge*
- Educational resources about EPI and CREON
*Eligibility: Available to patients with commercial prescription insurance coverage for CREON® (pancrelipase) who meet eligibility criteria. Neither co-pay assistance nor multivitamins/nutritional supplements are available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offers subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit
or call 1-844-662-7366 for additional information. For full Terms and Conditions for CREON CF patients, visit
or call 1-855-227-3493 for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit