How should I take CREON?
CREON should be taken with every meal and snack
Take CREON every time you eat to replace the enzymes your pancreas isn't making if you have EPI (exocrine pancreatic insufficiency). CREON works only when taken with food.
How much CREON should I take?
Your doctor will let you know how much CREON you need to take during each meal. Usually, half of your prescribed CREON dose should be taken with each snack.
Every meal
Every snack
Every day
Key points to remember when taking CREON:
- Swallow CREON capsules whole
Swallow CREON capsules whole and take them with enough liquid to swallow them right away. If you have trouble swallowing capsules, open the capsules and sprinkle the contents on a small amount of room-temperature, acidic food, like applesauce, bananas, or plain Greek yogurt. Drink enough liquid to make sure the medicine is swallowed completely. Ask your doctor about other foods you can mix with CREON. - Do not crush or chew CREON
Swallow CREON whole. Crushing, chewing, or holding the CREON capsules in your mouth may irritate your mouth or change the way CREON works in your body. - Do not store food mixed with CREON
If you sprinkle CREON on food, swallow it right after you mix it. Do not store CREON that has been mixed with food. - Do not make up for missed doses
If you forget to take your dose of CREON, call your doctor or wait until your next meal or snack and take your usual number of capsules. Take your next dose at your usual time. Do not make up for missed doses.
Safety Considerations:
CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. Call your healthcare professional (HCP) right away if you have any unusual or severe stomach pain; worsening of gout; pain, stiffness, redness or swelling of your joints; trouble with breathing; skin rashes; swollen lips; or itching. When taking CREON, it’s important to follow the dosing instructions provided by your HCP. Always take CREON with food. Do not crush or chew CREON capsules or the contents of the capsules, as this may cause mouth irritation.
Your CREON dose is tailored for you
Find out how you and your doctor can work together to find a CREON dose that works for you.
Record your treatment experience and daily routine using the Treatment Tracker.
Keep a record of your symptoms after you begin CREON treatment
While you’re taking CREON, keep track of any symptoms you’re experiencing with the
, and share this information with your doctor at your next in-person or telehealth appointment. It will help your doctor determine if your dose needs to be adjusted.
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Answers to frequently asked questions
Making healthy choices with EPI
There are certain changes you may need to make to your diet and lifestyle if you have EPI, even if you're taking CREON.