What to expect when you start taking CREON
Starting CREON is the beginning of a journey. Your doctor will tell you exactly how to take CREON, but here are helpful tips.

Making CREON part of your routine
Take CREON with every meal and snack
Whether it’s a full meal or a snack, take CREON every time you eat. Remember to follow your treatment plan closely and take CREON exactly as prescribed. Try creating some kind of memory device, such as a rhyme or repetition (eg, “Take CREON everywhere for every meal and every snack”) that helps you remember your medication. If you miss a dose, don’t double up; just take it with your next meal or snack.
Always have CREON: Take it on the go and enroll in automatic refills
Plan ahead for when you’re on the go by keeping CREON in your purse, in your backpack, or at your work desk. Just remember to store CREON in the original container in a cool, dry place. Automatic refills help ensure that you always have CREON when you need it.
Understand that your first dose is a starting point
Remember that getting used to CREON may take some time and a dose adjustment might be needed. That's why communicating with your doctor about your symptoms is so important.
Get the support you need, when you need it
CREON offers patient support programs for patients living with EPI.

I take CREON anytime I eat. My dose is larger for a meal versus a small snack. Taking CREON easily fits in my schedule as I just think of it as part of my meals now.
-VANESSA J. EPI patient
Your quick guide to EPI and CREON
It may seem like there's a lot to learn about EPI and CREON, but this brochure can help you navigate a variety of topics and provide you with the answers you need as you're starting treatment.
Making healthy diet and lifestyle choices
In addition to taking CREON to help manage your EPI, you may also need to change your diet and lifestyle habits. Work with your doctor to create a plan.
Healthy eating with EPI
EPI affects how well you absorb nutrients, so it’s especially important to eat nutritious food. Remember to take CREON with every meal and snack, as it replaces the enzymes your pancreas no longer makes and helps you break down food.
*These diet recommendations are not intended for people with EPI due to cystic fibrosis, who may have very different and specific nutritional needs.
Taking vitamins and supplements
With EPI, getting all the vitamins you need may take more than just eating well.
- Your doctor may prescribe supplements of the fat-soluble vitamins A, D, E, and K.
- Take them as directed.
By enrolling in a
, you may be able to receive multivitamins and nutritional products at no charge.†
Making lifestyle changes
It is important to adopt healthy habits. In addition to eating a well-balanced diet, consider limiting alcohol use and quitting smoking.
†Eligibility: Available to patients with commercial prescription insurance coverage for CREON® (pancrelipase) who meet eligibility criteria. Neither co-pay assistance nor multivitamins/nutritional supplements are available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offers subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit
or call 1-844-662-7366 for additional information. For full Terms and Conditions for CREON CF patients, visit
or call 1-855-227-3493 for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit