How does CREON work?

CREON replaces pancreatic enzymes

CREON (pancrelipase) is a pancreatic enzyme replacement therapy, or PERT, that works by replacing the 3 pancreatic enzymes normally made by a healthy pancreas.

Your pancreas normally releases these enzymes every time you eat, which is why you need to take CREON every time you eat. Timing is key. For CREON to work as expected, it needs to be taken with every meal and snack.




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breaks down

breaks down carbohydrates (sugars)

breaks down

I take 3 CREON capsules with every meal and 2 capsules with every snack. I carry CREON with me everywhere I go. I remember to bring my CREON with me because I know how important it is for managing malabsorption.

- Mark B. EPI patient

Still not exactly sure how CREON works?

Watch this short video to get a better idea and see why CREON needs to be “on board” with your food.

Record your treatment progress and daily routine using the Treatment Tracker.

Answers to frequently asked questions

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CREON dosing

If your doctor prescribes you CREON, they will choose a dose that is specific for you based on different factors.