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How to Take CREON
Infants

Giving CREON to your infant up to 12 months old

CREON may be prescribed to infants who have EPI (exocrine pancreatic insufficiency). If you’re caring for an infant who needs to take CREON, watch the video for tips on giving enzymes to a baby.

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Sprinkling Instructions

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Hold the capsule upright so that you can see the word CREON on the capsule.

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Carefully twist off the top portion of the capsule.

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Sprinkle the contents from the capsule directly into your infant’s mouth, or mix the contents in a small amount of room-temperature acidic soft food like applesauce, bananas, or plain Greek yogurt. Do not mix CREON with formula or bottled breast milk. If you sprinkle CREON on soft food, feed it to your child immediately. Do not store leftover food mixed with CREON.

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Give your child enough liquid to completely swallow the CREON contents or the CREON and food mixture. Check inside your baby’s mouth to ensure that he or she has swallowed all the capsule contents. To avoid irritation, care should be taken to ensure no medicine is left in the mouth. Refer to the CREON Medication Guide for additional instructions.

Key points to remember when giving CREON to infants:

  • Give CREON right before every feeding of formula, breast milk, or food.
  • Do not crush or chew CREON capsules or their contents.
  • Do not mix the CREON capsule contents directly into formula or breast milk.
  • Give your infant enough formula or breast milk to help him or her completely swallow the CREON capsule contents or CREON food mixture.
  • Check inside your baby’s mouth to ensure that he or she has swallowed all the CREON capsule contents. To avoid irritation, care should be taken to ensure no medicine is left in the mouth.
  • If you sprinkle CREON on food, give the CREON and food mixture to your infant right away. Do not save leftover food mixed with CREON.
  • CREON needs to be stored and dispensed in the original container to protect from moisture. If there is a moisture-absorbing packet (desiccant) in the bottle, keep it in the bottle. Do not throw it away.

 

Safety Considerations:
CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. Call your healthcare professional (HCP) right away if you have any unusual or severe stomach pain; worsening of gout; pain, stiffness, redness or swelling of your joints; trouble with breathing; skin rashes; swollen lips; or itching. When taking CREON, it’s important to follow the dosing instructions provided by your HCP. Always take CREON with food. Do not crush or chew CREON capsules or the contents of the capsules, as this may cause mouth irritation.

Answers to frequently asked questions

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CREON patient videos

Hear real patients talk about their experiences with EPI and CREON.

Watch videos