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CREON (pancrelipase) is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes. This condition is called EPI (exocrine pancreatic insufficiency) and may be due to cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions.

CREON Number 1 Prescribed EPI Treatment
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Understanding EPI

See how EPI can affect the digestion and absorption of nutrients.

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Getting started with CREON

Get tools and tips to help you start and stay on track with your CREON treatment plan.

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Taking CREON

Review important reminders for taking CREON, such as how and when to take it.

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Saving on CREON

Find out if you’re eligible to pay as little as $5 (or less) for your monthly CREON prescription.*

Question circle

Answer this question so we can help you find what you're looking for:

How long have you been taking CREON?

You answered "0 to 3 months"

Record your treatment progress and daily routine using the Treatment Tracker.

Learn about the financial, multivitamin, and educational resources available through CREON On Course.

You answered "3 months to a few years"

Get tools and tips to help you start and stay on track with your CREON treatment plan.

Read about how to make healthy diet and lifestyle choices with EPI.

You answered "Whole life"

Learn about the financial, multivitamin, and educational resources available through CFCareForward.

Hear people with EPI due to cystic fibrosis talk about their experiences with CREON.

You answered "Not prescribed CREON"

Fill out the Doctor Discussion Guide to help you communicate your symptoms to your doctor.

Learn how CREON works to break down food in people with EPI.

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Supporting you every step of the way

CREON's patient support programs provide you with:

  • Financial savings on CREON*
  • Multivitamins and nutritional products at no charge*
  • Educational resources about EPI and CREON

*Eligibility: Available to patients with commercial prescription insurance coverage for CREON® (pancrelipase) who meet eligibility criteria. Neither co-pay assistance nor multivitamins/nutritional supplements are available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offers subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit

 or call 1-844-662-7366 for additional information. For full Terms and Conditions for CREON CF patients, visit

 or call 1-855-227-3493 for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit